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Effect of i.p. insulin administration on IGF1 and IGFBP1 in type 1 diabetes
In type 1 diabetes mellitus (T1DM), low concentrations of IGF1 and high concentrations of IGF-binding protein 1 (IGFBP1) have been reported. It has been suggested that these abnormalities in the GH–IGF1 axis are due to low insulin concentrations in the portal vein. We hypothesized that the i.p. rout...
Autores principales: | van Dijk, P R, Logtenberg, S J J, Groenier, K H, Kleefstra, N, Bilo, H J G, Arnqvist, H J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899582/ https://www.ncbi.nlm.nih.gov/pubmed/24327601 http://dx.doi.org/10.1530/EC-13-0089 |
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