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NMDA receptor activation requires remodeling of inter-subunit contacts within ligand-binding heterodimers

Two classes of glutamate-activated channels mediate excitation at central synapses: N-methyl-d-aspartic acid (NMDA) receptors and non-NMDA receptors. Despite substantial structural homology, each class generates signals with characteristic kinetics and mediates distinct synaptic functions. In non-NM...

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Detalles Bibliográficos
Autores principales: Borschel, William F, Murthy, Swetha E, Kasperek, Eileen M, Popescu, Gabriela K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899702/
https://www.ncbi.nlm.nih.gov/pubmed/21988914
http://dx.doi.org/10.1038/ncomms1512