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A model of hematopoietic stem cell proliferation under the influence of a chemotherapeutic agent in combination with a hematopoietic inducing agent
BACKGROUND: Hematopoiesis is a complex process that encompasses both pro-mitotic and anti-mitotic stimuli. Pharmacological agents used in chemotherapy have a prominent anti-mitotic effect. The approach of inhibiting cell proliferation is rational with respect to the rapidly dividing malignant cells....
Autores principales: | Mouser, Christina L, Antoniou, Eliana S, Tadros, James, Vassiliou, Evros K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899742/ https://www.ncbi.nlm.nih.gov/pubmed/24438084 http://dx.doi.org/10.1186/1742-4682-11-4 |
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