Incidence of colorectal cancer in BRCA1 and BRCA2 mutation carriers: results from a follow-up study

BACKGROUND: The BRCA1 and BRCA2 genes confer increased susceptibility to breast and ovarian cancer and to a spectrum of other cancers. There is controversy regarding the risk of colorectal cancer conferred by germline mutations in these two genes. METHODS: We followed 7015 women with a BRCA mutation...

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Detalles Bibliográficos
Autores principales: Phelan, C M, Iqbal, J, Lynch, H T, Lubinski, J, Gronwald, J, Moller, P, Ghadirian, P, Foulkes, W D, Armel, S, Eisen, A, Neuhausen, S L, Senter, L, Singer, C F, Ainsworth, P, Kim-Sing, C, Tung, N, Llacuachaqui, M, Chornokur, G, Ping, S, Narod, S A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899769/
https://www.ncbi.nlm.nih.gov/pubmed/24292448
http://dx.doi.org/10.1038/bjc.2013.741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899769/
https://www.ncbi.nlm.nih.gov/pubmed/24292448
http://dx.doi.org/10.1038/bjc.2013.741

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