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Gambogic acid synergistically potentiates cisplatin-induced apoptosis in non-small-cell lung cancer through suppressing NF-κB and MAPK/HO-1 signalling
BACKGROUND: Gambogic acid (GA) has been reported to have potent anticancer activity and is authorised to be tested in phase II clinical trials for treatment of non-small-cell lung cancer (NSCLC). The present study aims to investigate whether GA would be synergistic with cisplatin (CDDP) against the...
Autores principales: | Wang, L-H, Li, Y, Yang, S-N, Wang, F-Y, Hou, Y, Cui, W, Chen, K, Cao, Q, Wang, S, Zhang, T-Y, Wang, Z-Z, Xiao, W, Yang, J-Y, Wu, C-F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899775/ https://www.ncbi.nlm.nih.gov/pubmed/24300974 http://dx.doi.org/10.1038/bjc.2013.752 |
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