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High SINE RNA Expression Correlates with Post-Transcriptional Downregulation of BRCA1

Short Interspersed Nuclear Elements (SINEs) are non-autonomous retrotransposons that comprise a large fraction of the human genome. SINEs are demethylated in human disease, but whether SINEs become transcriptionally induced and how the resulting transcripts may affect the expression of protein codin...

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Detalles Bibliográficos
Autores principales: Peterson, Maureen, Chandler, Vicki L., Bosco, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899967/
https://www.ncbi.nlm.nih.gov/pubmed/24705161
http://dx.doi.org/10.3390/genes4020226