Transgenic Models of Spinocerebellar Ataxia Type 10: Modeling a Repeat Expansion Disorder

Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant neurodegenerative disease with a spectrum of phenotypes. SCA10 is caused by a pentanucleotide repeat expansion of the ATTCT motif within intron 9 of ATAXIN 10 (ATXN10). Patients present with cerebellar ataxia; however, a subset also dev...

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Detalles Bibliográficos
Autores principales: McFarland, Karen N., Ashizawa, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899997/
https://www.ncbi.nlm.nih.gov/pubmed/24533179
http://dx.doi.org/10.3390/genes3030481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899997/
https://www.ncbi.nlm.nih.gov/pubmed/24533179
http://dx.doi.org/10.3390/genes3030481

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