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Transgenic Models of Spinocerebellar Ataxia Type 10: Modeling a Repeat Expansion Disorder
Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant neurodegenerative disease with a spectrum of phenotypes. SCA10 is caused by a pentanucleotide repeat expansion of the ATTCT motif within intron 9 of ATAXIN 10 (ATXN10). Patients present with cerebellar ataxia; however, a subset also dev...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899997/ https://www.ncbi.nlm.nih.gov/pubmed/24533179 http://dx.doi.org/10.3390/genes3030481 |