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Warfarin-Amiodarone Drug-Drug Interactions: Determination of [I](u)/K(I),(u) for Amiodarone and its Plasma Metabolites
A retrospective clinical evaluation in a cohort of 73 patients receiving stable anticoagulation therapy showed that the addition/elimination of amiodarone resulted in a 6–65% change in warfarin dose requirement. To evaluate the roles of amiodarone and its circulating metabolites in this highly varia...
Autores principales: | McDonald, MG, Au, NT, Wittkowsky, AK, Rettie, AE |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900249/ https://www.ncbi.nlm.nih.gov/pubmed/22398967 http://dx.doi.org/10.1038/clpt.2011.283 |
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