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Obesity and dyslipidemia in patients with psoriasis treated at a dermatologic clinic in Manaus

BACKGROUND: Psoriasis is a chronic inflammatory disease of multifactorial etiology, with participation of genetic, autoimmune and environmental factors. Recent studies have demonstrated the role of inflammatory cells and mediators in the pathogenesis of psoriasis, which is now defined as a systemic...

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Autores principales: Santos, Mônica, Fonseca, Hannah Monteiro, Jalkh, Alex Panizza, Gomes, Gabriela Piraice, Cavalcante, Andrea de Souza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900341/
https://www.ncbi.nlm.nih.gov/pubmed/24474099
http://dx.doi.org/10.1590/abd1806-4841.20132090
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author Santos, Mônica
Fonseca, Hannah Monteiro
Jalkh, Alex Panizza
Gomes, Gabriela Piraice
Cavalcante, Andrea de Souza
author_facet Santos, Mônica
Fonseca, Hannah Monteiro
Jalkh, Alex Panizza
Gomes, Gabriela Piraice
Cavalcante, Andrea de Souza
author_sort Santos, Mônica
collection PubMed
description BACKGROUND: Psoriasis is a chronic inflammatory disease of multifactorial etiology, with participation of genetic, autoimmune and environmental factors. Recent studies have demonstrated the role of inflammatory cells and mediators in the pathogenesis of psoriasis, which is now defined as a systemic and autoimmune inflammatory disease that may be associated with other diseases of inflammatory nature. OBJECTIVES: To evaluate the occurrence of obesity and dyslipidemia in patients with psoriasis treated at a dermatology clinic in Manaus. METHODS: We performed a prospective descriptive study to assess the prevalence of obesity and dyslipidemia in patients with psoriasis. Besides the recommended dermatological care, a physical examination was performed to measure weight, height and waist circumference. RESULTS: We included 72 patients, 44 (61.1%) female and 28 (38.9%) male, with a mean age of 51.0 years ± 15.9 years. As for body mass index (BMI), 16 (22.2%) were overweight and 20 (27.8%) were obese. In the analysis of waist circumference in relation to gender, we found that 79.5% of women surveyed had central obesity, a percentage statistically higher than that observed among men (42.9%) at the 5% level of significance (p = 0.001). Regarding the diagnosis of dyslipidemia, 29 (65.9%) females and 22 (78.6%) males showed alterations in lipid profile. CONCLUSIONS: The occurrence of dyslipidemia and obesity in patients with psoriasis can affect life quality and expectancy, increasing the risk of systemic and metabolic diseases, which makes periodic investigation of these comorbidities in patients with psoriasis mandatory.
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spelling pubmed-39003412014-01-29 Obesity and dyslipidemia in patients with psoriasis treated at a dermatologic clinic in Manaus Santos, Mônica Fonseca, Hannah Monteiro Jalkh, Alex Panizza Gomes, Gabriela Piraice Cavalcante, Andrea de Souza An Bras Dermatol Investigation BACKGROUND: Psoriasis is a chronic inflammatory disease of multifactorial etiology, with participation of genetic, autoimmune and environmental factors. Recent studies have demonstrated the role of inflammatory cells and mediators in the pathogenesis of psoriasis, which is now defined as a systemic and autoimmune inflammatory disease that may be associated with other diseases of inflammatory nature. OBJECTIVES: To evaluate the occurrence of obesity and dyslipidemia in patients with psoriasis treated at a dermatology clinic in Manaus. METHODS: We performed a prospective descriptive study to assess the prevalence of obesity and dyslipidemia in patients with psoriasis. Besides the recommended dermatological care, a physical examination was performed to measure weight, height and waist circumference. RESULTS: We included 72 patients, 44 (61.1%) female and 28 (38.9%) male, with a mean age of 51.0 years ± 15.9 years. As for body mass index (BMI), 16 (22.2%) were overweight and 20 (27.8%) were obese. In the analysis of waist circumference in relation to gender, we found that 79.5% of women surveyed had central obesity, a percentage statistically higher than that observed among men (42.9%) at the 5% level of significance (p = 0.001). Regarding the diagnosis of dyslipidemia, 29 (65.9%) females and 22 (78.6%) males showed alterations in lipid profile. CONCLUSIONS: The occurrence of dyslipidemia and obesity in patients with psoriasis can affect life quality and expectancy, increasing the risk of systemic and metabolic diseases, which makes periodic investigation of these comorbidities in patients with psoriasis mandatory. Sociedade Brasileira de Dermatologia 2013 /pmc/articles/PMC3900341/ /pubmed/24474099 http://dx.doi.org/10.1590/abd1806-4841.20132090 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Investigation
Santos, Mônica
Fonseca, Hannah Monteiro
Jalkh, Alex Panizza
Gomes, Gabriela Piraice
Cavalcante, Andrea de Souza
Obesity and dyslipidemia in patients with psoriasis treated at a dermatologic clinic in Manaus
title Obesity and dyslipidemia in patients with psoriasis treated at a dermatologic clinic in Manaus
title_full Obesity and dyslipidemia in patients with psoriasis treated at a dermatologic clinic in Manaus
title_fullStr Obesity and dyslipidemia in patients with psoriasis treated at a dermatologic clinic in Manaus
title_full_unstemmed Obesity and dyslipidemia in patients with psoriasis treated at a dermatologic clinic in Manaus
title_short Obesity and dyslipidemia in patients with psoriasis treated at a dermatologic clinic in Manaus
title_sort obesity and dyslipidemia in patients with psoriasis treated at a dermatologic clinic in manaus
topic Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900341/
https://www.ncbi.nlm.nih.gov/pubmed/24474099
http://dx.doi.org/10.1590/abd1806-4841.20132090
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