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Obesity and dyslipidemia in patients with psoriasis treated at a dermatologic clinic in Manaus
BACKGROUND: Psoriasis is a chronic inflammatory disease of multifactorial etiology, with participation of genetic, autoimmune and environmental factors. Recent studies have demonstrated the role of inflammatory cells and mediators in the pathogenesis of psoriasis, which is now defined as a systemic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Dermatologia
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900341/ https://www.ncbi.nlm.nih.gov/pubmed/24474099 http://dx.doi.org/10.1590/abd1806-4841.20132090 |
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author | Santos, Mônica Fonseca, Hannah Monteiro Jalkh, Alex Panizza Gomes, Gabriela Piraice Cavalcante, Andrea de Souza |
author_facet | Santos, Mônica Fonseca, Hannah Monteiro Jalkh, Alex Panizza Gomes, Gabriela Piraice Cavalcante, Andrea de Souza |
author_sort | Santos, Mônica |
collection | PubMed |
description | BACKGROUND: Psoriasis is a chronic inflammatory disease of multifactorial etiology, with participation of genetic, autoimmune and environmental factors. Recent studies have demonstrated the role of inflammatory cells and mediators in the pathogenesis of psoriasis, which is now defined as a systemic and autoimmune inflammatory disease that may be associated with other diseases of inflammatory nature. OBJECTIVES: To evaluate the occurrence of obesity and dyslipidemia in patients with psoriasis treated at a dermatology clinic in Manaus. METHODS: We performed a prospective descriptive study to assess the prevalence of obesity and dyslipidemia in patients with psoriasis. Besides the recommended dermatological care, a physical examination was performed to measure weight, height and waist circumference. RESULTS: We included 72 patients, 44 (61.1%) female and 28 (38.9%) male, with a mean age of 51.0 years ± 15.9 years. As for body mass index (BMI), 16 (22.2%) were overweight and 20 (27.8%) were obese. In the analysis of waist circumference in relation to gender, we found that 79.5% of women surveyed had central obesity, a percentage statistically higher than that observed among men (42.9%) at the 5% level of significance (p = 0.001). Regarding the diagnosis of dyslipidemia, 29 (65.9%) females and 22 (78.6%) males showed alterations in lipid profile. CONCLUSIONS: The occurrence of dyslipidemia and obesity in patients with psoriasis can affect life quality and expectancy, increasing the risk of systemic and metabolic diseases, which makes periodic investigation of these comorbidities in patients with psoriasis mandatory. |
format | Online Article Text |
id | pubmed-3900341 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-39003412014-01-29 Obesity and dyslipidemia in patients with psoriasis treated at a dermatologic clinic in Manaus Santos, Mônica Fonseca, Hannah Monteiro Jalkh, Alex Panizza Gomes, Gabriela Piraice Cavalcante, Andrea de Souza An Bras Dermatol Investigation BACKGROUND: Psoriasis is a chronic inflammatory disease of multifactorial etiology, with participation of genetic, autoimmune and environmental factors. Recent studies have demonstrated the role of inflammatory cells and mediators in the pathogenesis of psoriasis, which is now defined as a systemic and autoimmune inflammatory disease that may be associated with other diseases of inflammatory nature. OBJECTIVES: To evaluate the occurrence of obesity and dyslipidemia in patients with psoriasis treated at a dermatology clinic in Manaus. METHODS: We performed a prospective descriptive study to assess the prevalence of obesity and dyslipidemia in patients with psoriasis. Besides the recommended dermatological care, a physical examination was performed to measure weight, height and waist circumference. RESULTS: We included 72 patients, 44 (61.1%) female and 28 (38.9%) male, with a mean age of 51.0 years ± 15.9 years. As for body mass index (BMI), 16 (22.2%) were overweight and 20 (27.8%) were obese. In the analysis of waist circumference in relation to gender, we found that 79.5% of women surveyed had central obesity, a percentage statistically higher than that observed among men (42.9%) at the 5% level of significance (p = 0.001). Regarding the diagnosis of dyslipidemia, 29 (65.9%) females and 22 (78.6%) males showed alterations in lipid profile. CONCLUSIONS: The occurrence of dyslipidemia and obesity in patients with psoriasis can affect life quality and expectancy, increasing the risk of systemic and metabolic diseases, which makes periodic investigation of these comorbidities in patients with psoriasis mandatory. Sociedade Brasileira de Dermatologia 2013 /pmc/articles/PMC3900341/ /pubmed/24474099 http://dx.doi.org/10.1590/abd1806-4841.20132090 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Investigation Santos, Mônica Fonseca, Hannah Monteiro Jalkh, Alex Panizza Gomes, Gabriela Piraice Cavalcante, Andrea de Souza Obesity and dyslipidemia in patients with psoriasis treated at a dermatologic clinic in Manaus |
title | Obesity and dyslipidemia in patients with psoriasis treated at a
dermatologic clinic in Manaus
|
title_full | Obesity and dyslipidemia in patients with psoriasis treated at a
dermatologic clinic in Manaus
|
title_fullStr | Obesity and dyslipidemia in patients with psoriasis treated at a
dermatologic clinic in Manaus
|
title_full_unstemmed | Obesity and dyslipidemia in patients with psoriasis treated at a
dermatologic clinic in Manaus
|
title_short | Obesity and dyslipidemia in patients with psoriasis treated at a
dermatologic clinic in Manaus
|
title_sort | obesity and dyslipidemia in patients with psoriasis treated at a
dermatologic clinic in manaus |
topic | Investigation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900341/ https://www.ncbi.nlm.nih.gov/pubmed/24474099 http://dx.doi.org/10.1590/abd1806-4841.20132090 |
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