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Cutaneous lesions and finger clubbing uncovering hypocomplementemic urticarial vasculitis and hepatitis C with mixed cryoglobulinemia
Urticarial vasculitis is a rare clinicopathologic entity characterized by urticarial lesions that persist for more than 24 hours and histologic features of leukocytoclastic vasculitis. Patients can be divided into normocomplementemic or hypocomplementemic. The authors report the case of a healthy 49...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Sociedade Brasileira de Dermatologia
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900351/ https://www.ncbi.nlm.nih.gov/pubmed/24474109 http://dx.doi.org/10.1590/abd1806-4841.20132776 |
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author | Pinto-Almeida, Teresa Caetano, Mónica Alves, Rosário Selores, Manuela |
author_facet | Pinto-Almeida, Teresa Caetano, Mónica Alves, Rosário Selores, Manuela |
author_sort | Pinto-Almeida, Teresa |
collection | PubMed |
description | Urticarial vasculitis is a rare clinicopathologic entity characterized by urticarial lesions that persist for more than 24 hours and histologic features of leukocytoclastic vasculitis. Patients can be divided into normocomplementemic or hypocomplementemic. The authors report the case of a healthy 49-year-old woman with a 1-year history of highly pruritic generalized cutaneous lesions and finger clubbing. Laboratory tests together with histopathologic examination allowed the diagnosis of hypocomplementemic urticarial vasculitis, chronic hepatitis C and type II mixed cryoglobulinemia. The patient started symptomatic treatment and was referred to a gastroenterologist for management of the hepatitis C, with progressive improvement of the skin condition. The development of hypocomplementemic urticarial vasculitis in the context of chronic hepatitis C is exceedingly rare and possible pathogenic mechanisms are discussed. |
format | Online Article Text |
id | pubmed-3900351 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-39003512014-01-29 Cutaneous lesions and finger clubbing uncovering hypocomplementemic urticarial vasculitis and hepatitis C with mixed cryoglobulinemia Pinto-Almeida, Teresa Caetano, Mónica Alves, Rosário Selores, Manuela An Bras Dermatol Case Report Urticarial vasculitis is a rare clinicopathologic entity characterized by urticarial lesions that persist for more than 24 hours and histologic features of leukocytoclastic vasculitis. Patients can be divided into normocomplementemic or hypocomplementemic. The authors report the case of a healthy 49-year-old woman with a 1-year history of highly pruritic generalized cutaneous lesions and finger clubbing. Laboratory tests together with histopathologic examination allowed the diagnosis of hypocomplementemic urticarial vasculitis, chronic hepatitis C and type II mixed cryoglobulinemia. The patient started symptomatic treatment and was referred to a gastroenterologist for management of the hepatitis C, with progressive improvement of the skin condition. The development of hypocomplementemic urticarial vasculitis in the context of chronic hepatitis C is exceedingly rare and possible pathogenic mechanisms are discussed. Sociedade Brasileira de Dermatologia 2013 /pmc/articles/PMC3900351/ /pubmed/24474109 http://dx.doi.org/10.1590/abd1806-4841.20132776 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Pinto-Almeida, Teresa Caetano, Mónica Alves, Rosário Selores, Manuela Cutaneous lesions and finger clubbing uncovering hypocomplementemic urticarial vasculitis and hepatitis C with mixed cryoglobulinemia |
title | Cutaneous lesions and finger clubbing uncovering hypocomplementemic
urticarial vasculitis and hepatitis C with mixed cryoglobulinemia
|
title_full | Cutaneous lesions and finger clubbing uncovering hypocomplementemic
urticarial vasculitis and hepatitis C with mixed cryoglobulinemia
|
title_fullStr | Cutaneous lesions and finger clubbing uncovering hypocomplementemic
urticarial vasculitis and hepatitis C with mixed cryoglobulinemia
|
title_full_unstemmed | Cutaneous lesions and finger clubbing uncovering hypocomplementemic
urticarial vasculitis and hepatitis C with mixed cryoglobulinemia
|
title_short | Cutaneous lesions and finger clubbing uncovering hypocomplementemic
urticarial vasculitis and hepatitis C with mixed cryoglobulinemia
|
title_sort | cutaneous lesions and finger clubbing uncovering hypocomplementemic
urticarial vasculitis and hepatitis c with mixed cryoglobulinemia |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900351/ https://www.ncbi.nlm.nih.gov/pubmed/24474109 http://dx.doi.org/10.1590/abd1806-4841.20132776 |
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