An Allosteric Signaling Pathway of Human 3-Phosphoglycerate Kinase from Force Distribution Analysis

3-Phosphogycerate kinase (PGK) is a two domain enzyme, which transfers a phosphate group between its two substrates, 1,3-bisphosphoglycerate bound to the N-domain and ADP bound to the C-domain. Indispensable for the phosphoryl transfer reaction is a large conformational change from an inactive open...

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Detalles Bibliográficos
Autores principales: Palmai, Zoltan, Seifert, Christian, Gräter, Frauke, Balog, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900376/
https://www.ncbi.nlm.nih.gov/pubmed/24465199
http://dx.doi.org/10.1371/journal.pcbi.1003444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900376/
https://www.ncbi.nlm.nih.gov/pubmed/24465199
http://dx.doi.org/10.1371/journal.pcbi.1003444

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