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Molecular and Genetic Characterization of Natural HIV-1 Tat Exon-1 Variants from North India and Their Functional Implications

BACKGROUND: Designing an ideal vaccine against HIV-1 has been difficult due to enormous genetic variability as a result of high replication rate and lack of proofreading activity of reverse transcriptase leading to emergence of genetic variants and recombinants. Tat transactivates HIV-1 LTR, resulti...

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Detalles Bibliográficos
Autores principales:	Ronsard, Larance, Lata, Sneh, Singh, Jyotsna, Ramachandran, Vishnampettai G., Das, Shukla, Banerjea, Akhil C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900424/ https://www.ncbi.nlm.nih.gov/pubmed/24465566 http://dx.doi.org/10.1371/journal.pone.0085452

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