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Crystal Structure of the Lamprey Variable Lymphocyte Receptor C Reveals an Unusual Feature in Its N-Terminal Capping Module

Jawless vertebrates represented by lampreys and hagfish use variable lymphocyte receptors (VLRs) as antigen receptors to mount adaptive immune responses. VLRs generate diversity that is comparable to immunoglobulins and T-cell receptors by a gene conversion-like mechanism, which is mediated by cytos...

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Detalles Bibliográficos
Autores principales: Kanda, Ryo, Sutoh, Yoichi, Kasamatsu, Jun, Maenaka, Katsumi, Kasahara, Masanori, Ose, Toyoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900441/
https://www.ncbi.nlm.nih.gov/pubmed/24465760
http://dx.doi.org/10.1371/journal.pone.0085875