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G(0)-G(1) Transition and the Restriction Point in Pancreatic β-Cells In Vivo

Most of our knowledge on cell kinetics stems from in vitro studies of continuously dividing cells. In this study, we determine in vivo cell-cycle parameters of pancreatic β-cells, a largely quiescent population, using drugs that mimic or prevent glucose-induced replication of β-cells in mice. Quiesc...

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Detalles Bibliográficos
Autores principales:	Hija, Ayat, Salpeter, Seth, Klochendler, Agnes, Grimsby, Joseph, Brandeis, Michael, Glaser, Benjamin, Dor, Yuval
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2014
Materias:	Islet Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900543/ https://www.ncbi.nlm.nih.gov/pubmed/24130333 http://dx.doi.org/10.2337/db12-1035

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