Developmental Programming by Maternal Insulin Resistance: Hyperinsulinemia, Glucose Intolerance, and Dysregulated Lipid Metabolism in Male Offspring of Insulin-Resistant Mice

Maternal obesity and gestational diabetes mellitus (GDM) are associated with obesity and diabetes risk in offspring. We tested whether maternal insulin resistance, which frequently coexists with GDM and obesity, could independently contribute to dysregulation of offspring metabolism. Female mice hap...

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Detalles Bibliográficos
Autores principales: Isganaitis, Elvira, Woo, Melissa, Ma, Huijuan, Chen, Michael, Kong, Wen, Lytras, Aristides, Sales, Vicencia, DeCoste-Lopez, Jennifer, Lee, Kyung-Ju, Leatherwood, Cianna, Lee, Deborah, Fitzpatrick, Connor, Gall, Walter, Watkins, Steven, Patti, Mary-Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900545/
https://www.ncbi.nlm.nih.gov/pubmed/24186867
http://dx.doi.org/10.2337/db13-0558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900545/
https://www.ncbi.nlm.nih.gov/pubmed/24186867
http://dx.doi.org/10.2337/db13-0558

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