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Comparative Effects of Prolonged and Intermittent Stimulation of the Glucagon-Like Peptide 1 Receptor on Gastric Emptying and Glycemia

Acute administration of glucagon-like peptide 1 (GLP-1) and its agonists slows gastric emptying, which represents the major mechanism underlying their attenuation of postprandial glycemic excursions. However, this effect may diminish during prolonged use. We compared the effects of prolonged and int...

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Detalles Bibliográficos
Autores principales: Umapathysivam, Mahesh M., Lee, Michael Y., Jones, Karen L., Annink, Christopher E., Cousins, Caroline E., Trahair, Laurence G., Rayner, Chris K., Chapman, Marianne J., Nauck, Michael A., Horowitz, Michael, Deane, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900552/
https://www.ncbi.nlm.nih.gov/pubmed/24089511
http://dx.doi.org/10.2337/db13-0893