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Protective Effects of Membrane-Anchored and Secreted DNA Vaccines Encoding Fatty Acid-Binding Protein and Glutathione S-Transferase against Schistosoma japonicum

In order to explore the high performance bivalent DNA-based vaccine against schistosomes, SjFABP and Sj26GST were selected and used to construct a vaccine. Two strategies were used to construct the bivalent DNA vaccine. In the first strategy, a plasmid encoding antigen in the secreted form was used,...

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Detalles Bibliográficos
Autores principales: Tu, Yaqin, Hu, Yang, Fan, Guorun, Chen, Zhihao, Liu, Lin, Man, Dandan, Liu, Shuojie, Tang, Chengwu, Zhang, Yin, Dai, Wuxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900569/
https://www.ncbi.nlm.nih.gov/pubmed/24466157
http://dx.doi.org/10.1371/journal.pone.0086575