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Protective Effects of Membrane-Anchored and Secreted DNA Vaccines Encoding Fatty Acid-Binding Protein and Glutathione S-Transferase against Schistosoma japonicum
In order to explore the high performance bivalent DNA-based vaccine against schistosomes, SjFABP and Sj26GST were selected and used to construct a vaccine. Two strategies were used to construct the bivalent DNA vaccine. In the first strategy, a plasmid encoding antigen in the secreted form was used,...
Autores principales: | Tu, Yaqin, Hu, Yang, Fan, Guorun, Chen, Zhihao, Liu, Lin, Man, Dandan, Liu, Shuojie, Tang, Chengwu, Zhang, Yin, Dai, Wuxing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900569/ https://www.ncbi.nlm.nih.gov/pubmed/24466157 http://dx.doi.org/10.1371/journal.pone.0086575 |
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