Detection of Novel Visible-Light Region Absorbance Peaks in the Urine after Alkalization in Patients with Alkaptonuria

BACKGROUND: Alkaptonuria, caused by a deficiency of homogentisate 1,2-dioxygenase, results in the accumulation of homogentisic acid (2,5-dihydroxyphenylacetic acid, HGA) in the urine. Alkaptonuria is suspected when the urine changes color after it is left to stand at room temperature for several hou...

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Detalles Bibliográficos
Autores principales: Tokuhara, Yasunori, Shukuya, Kenichi, Tanaka, Masami, Mouri, Mariko, Ohkawa, Ryunosuke, Fujishiro, Midori, Takahashi, Tomoo, Okubo, Shigeo, Yokota, Hiromitsu, Kurano, Makoto, Ikeda, Hitoshi, Yamaguchi, Seiji, Inagaki, Shinobu, Ishige-Wada, Mika, Usui, Hiromi, Yatomi, Yutaka, Shimosawa, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900575/
https://www.ncbi.nlm.nih.gov/pubmed/24466168
http://dx.doi.org/10.1371/journal.pone.0086606

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