Regulatory T Cell Ablation Causes Acute T Cell Lymphopenia

Regulatory T (Treg) cells enforce T cell homeostasis and maintain peripheral T cell tolerance. Here we report a previously unappreciated phenomenon of acute T cell lymphopenia in secondary lymphoid organs and non-lymphoid tissues triggered by Treg cell depletion that precedes the expansion of self-r...

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Detalles Bibliográficos
Autores principales: Moltedo, Bruno, Hemmers, Saskia, Rudensky, Alexander Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900634/
https://www.ncbi.nlm.nih.gov/pubmed/24466225
http://dx.doi.org/10.1371/journal.pone.0086762

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