Enigma Prevents Cbl-c-Mediated Ubiquitination and Degradation of RETMEN2A

The Cbl proteins (Cbl, Cbl-b, and Cbl-c) are a highly conserved family of RING finger ubiquitin ligases (E3s) that function as negative regulators of tyrosine kinases in a wide variety of signal transduction pathways. In this study, we identify a new Cbl-c interacting protein, Enigma (PDLIM7). This...

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Detalles Bibliográficos
Autores principales: Kales, Stephen C., Nau, Marion M., Merchant, Anand S., Lipkowitz, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900716/
https://www.ncbi.nlm.nih.gov/pubmed/24466333
http://dx.doi.org/10.1371/journal.pone.0087116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900716/
https://www.ncbi.nlm.nih.gov/pubmed/24466333
http://dx.doi.org/10.1371/journal.pone.0087116

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