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Regulation of the Hsp104 Middle Domain Activity Is Critical for Yeast Prion Propagation
Molecular chaperones play a significant role in preventing protein misfolding and aggregation. Indeed, some protein conformational disorders have been linked to changes in the chaperone network. Curiously, in yeast, chaperones also play a role in promoting prion maintenance and propagation. While ma...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900729/ https://www.ncbi.nlm.nih.gov/pubmed/24466354 http://dx.doi.org/10.1371/journal.pone.0087521 |