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Visualization of Protease Activity In Vivo Using an Activatable Photo-Acoustic Imaging Probe Based on CuS Nanoparticles

Herein, we for the first time report a novel activatable photoacoustic (PA) imaging nano-probe for in vivo detection of cancer-related matrix metalloproteinases (MMPs). A black hole quencher 3 (BHQ3) which absorbs red light is conjugated to near-infrared (NIR)-absorbing copper sulfide (CuS) nanopart...

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Detalles Bibliográficos
Autores principales: Yang, Kai, Zhu, Lei, Nie, Liming, Sun, Xiaolian, Cheng, Liang, Wu, Chenxi, Niu, Gang, Chen, Xiaoyuan, Liu, Zhuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900798/
https://www.ncbi.nlm.nih.gov/pubmed/24465271
http://dx.doi.org/10.7150/thno.7217