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Cytomegalovirus (CMV)-Specific Perforin and Granzyme B ELISPOT Assays Detect Reactivation of CMV Infection in Inflammatory Bowel Disease

The role of cytomegalovirus (CMV) infection in the pathogenesis and exacerbation of Inflammatory Bowel Disease (IBD) has been unresolved. Typically, the CMV genome remains dormant in infected cells, but a breakdown of immune surveillance can lead to re-activation of viral replication in the gut muco...

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Detalles Bibliográficos
Autores principales: Nowacki, Tobias M., Bettenworth, Dominik, Ross, Matthias, Heidemann, Jan, Lehmann, Paul V., Lügering, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901090/
https://www.ncbi.nlm.nih.gov/pubmed/24710412
http://dx.doi.org/10.3390/cells1020035