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Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins
Macroautophagy has important physiological roles and its cytoprotective or detrimental function is compromised in various diseases such as many cancers and metabolic diseases. However, the importance of autophagy for cell responses has also been demonstrated in many other physiological and pathologi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901093/ https://www.ncbi.nlm.nih.gov/pubmed/24710422 http://dx.doi.org/10.3390/cells1020168 |
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author | Demine, Stéphane Michel, Sébastien Vannuvel, Kayleen Wanet, Anaïs Renard, Patricia Arnould, Thierry |
author_facet | Demine, Stéphane Michel, Sébastien Vannuvel, Kayleen Wanet, Anaïs Renard, Patricia Arnould, Thierry |
author_sort | Demine, Stéphane |
collection | PubMed |
description | Macroautophagy has important physiological roles and its cytoprotective or detrimental function is compromised in various diseases such as many cancers and metabolic diseases. However, the importance of autophagy for cell responses has also been demonstrated in many other physiological and pathological situations. In this review, we discuss some of the recently discovered mechanisms involved in specific and unspecific autophagy related to mitochondrial dysfunction and organelle degradation, lipid metabolism and lipophagy as well as recent findings and evidence that link autophagy to unconventional protein secretion. |
format | Online Article Text |
id | pubmed-3901093 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-39010932014-04-07 Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins Demine, Stéphane Michel, Sébastien Vannuvel, Kayleen Wanet, Anaïs Renard, Patricia Arnould, Thierry Cells Review Macroautophagy has important physiological roles and its cytoprotective or detrimental function is compromised in various diseases such as many cancers and metabolic diseases. However, the importance of autophagy for cell responses has also been demonstrated in many other physiological and pathological situations. In this review, we discuss some of the recently discovered mechanisms involved in specific and unspecific autophagy related to mitochondrial dysfunction and organelle degradation, lipid metabolism and lipophagy as well as recent findings and evidence that link autophagy to unconventional protein secretion. MDPI 2012-06-20 /pmc/articles/PMC3901093/ /pubmed/24710422 http://dx.doi.org/10.3390/cells1020168 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Demine, Stéphane Michel, Sébastien Vannuvel, Kayleen Wanet, Anaïs Renard, Patricia Arnould, Thierry Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins |
title | Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins |
title_full | Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins |
title_fullStr | Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins |
title_full_unstemmed | Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins |
title_short | Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins |
title_sort | macroautophagy and cell responses related to mitochondrial dysfunction, lipid metabolism and unconventional secretion of proteins |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901093/ https://www.ncbi.nlm.nih.gov/pubmed/24710422 http://dx.doi.org/10.3390/cells1020168 |
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