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Unfolded Protein Responses With or Without Unfolded Proteins?
The endoplasmic reticulum (ER) is the site of secretory protein biogenesis. The ER quality control (QC) machinery, including chaperones, ensures the correct folding of secretory proteins. Mutant proteins and environmental stresses can overwhelm the available QC machinery. To prevent and resolve accu...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901143/ https://www.ncbi.nlm.nih.gov/pubmed/24710536 http://dx.doi.org/10.3390/cells1040926 |