Atlantinone A, a Meroterpenoid Produced by Penicillium ribeum and Several Cheese Associated Penicillium Species

Atlantinone A has been isolated from the psychrotolerant fungus Penicillium ribeum. The exact structure of the compound was confirmed by mass spectrometric and 1- and 2D NMR experiments. Atlantinone A was originally only produced upon chemical epigenetic manipulation of P. hirayamae, however in this...

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Autores principales: Dalsgaard, Petur W., Petersen, Bent O., Duus, Jens Ø., Zidorn, Christian, Frisvad, Jens C., Christophersen, Carsten, Larsen, Thomas O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901203/
https://www.ncbi.nlm.nih.gov/pubmed/24957375
http://dx.doi.org/10.3390/metabo2010214
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author Dalsgaard, Petur W.
Petersen, Bent O.
Duus, Jens Ø.
Zidorn, Christian
Frisvad, Jens C.
Christophersen, Carsten
Larsen, Thomas O.
author_facet Dalsgaard, Petur W.
Petersen, Bent O.
Duus, Jens Ø.
Zidorn, Christian
Frisvad, Jens C.
Christophersen, Carsten
Larsen, Thomas O.
author_sort Dalsgaard, Petur W.
collection PubMed
description Atlantinone A has been isolated from the psychrotolerant fungus Penicillium ribeum. The exact structure of the compound was confirmed by mass spectrometric and 1- and 2D NMR experiments. Atlantinone A was originally only produced upon chemical epigenetic manipulation of P. hirayamae, however in this study the compound was found to be produced at standard growth conditions by the following species; P. solitum, P. discolor, P. commune, P. caseifulvum, P. palitans, P. novae-zeelandiae and P. monticola. A biosynthetic pathway to atlantinone A starting from andrastin A is proposed.
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spelling pubmed-39012032014-05-27 Atlantinone A, a Meroterpenoid Produced by Penicillium ribeum and Several Cheese Associated Penicillium Species Dalsgaard, Petur W. Petersen, Bent O. Duus, Jens Ø. Zidorn, Christian Frisvad, Jens C. Christophersen, Carsten Larsen, Thomas O. Metabolites Article Atlantinone A has been isolated from the psychrotolerant fungus Penicillium ribeum. The exact structure of the compound was confirmed by mass spectrometric and 1- and 2D NMR experiments. Atlantinone A was originally only produced upon chemical epigenetic manipulation of P. hirayamae, however in this study the compound was found to be produced at standard growth conditions by the following species; P. solitum, P. discolor, P. commune, P. caseifulvum, P. palitans, P. novae-zeelandiae and P. monticola. A biosynthetic pathway to atlantinone A starting from andrastin A is proposed. MDPI 2012-02-23 /pmc/articles/PMC3901203/ /pubmed/24957375 http://dx.doi.org/10.3390/metabo2010214 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Dalsgaard, Petur W.
Petersen, Bent O.
Duus, Jens Ø.
Zidorn, Christian
Frisvad, Jens C.
Christophersen, Carsten
Larsen, Thomas O.
Atlantinone A, a Meroterpenoid Produced by Penicillium ribeum and Several Cheese Associated Penicillium Species
title Atlantinone A, a Meroterpenoid Produced by Penicillium ribeum and Several Cheese Associated Penicillium Species
title_full Atlantinone A, a Meroterpenoid Produced by Penicillium ribeum and Several Cheese Associated Penicillium Species
title_fullStr Atlantinone A, a Meroterpenoid Produced by Penicillium ribeum and Several Cheese Associated Penicillium Species
title_full_unstemmed Atlantinone A, a Meroterpenoid Produced by Penicillium ribeum and Several Cheese Associated Penicillium Species
title_short Atlantinone A, a Meroterpenoid Produced by Penicillium ribeum and Several Cheese Associated Penicillium Species
title_sort atlantinone a, a meroterpenoid produced by penicillium ribeum and several cheese associated penicillium species
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901203/
https://www.ncbi.nlm.nih.gov/pubmed/24957375
http://dx.doi.org/10.3390/metabo2010214
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