Cargando…
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-Monophosphate (AICAR), a Highly Conserved Purine Intermediate with Multiple Effects
AICAR (5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate) is a natural metabolic intermediate of purine biosynthesis that is present in all organisms. In yeast, AICAR plays important regulatory roles under physiological conditions, notably through its direct interactions wi...
Autores principales: | Daignan-Fornier, Bertrand, Pinson, Benoît |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901205/ https://www.ncbi.nlm.nih.gov/pubmed/24957512 http://dx.doi.org/10.3390/metabo2020292 |
Ejemplares similares
-
Yeast to Study Human Purine Metabolism Diseases
por: Daignan-Fornier, Bertrand, et al.
Publicado: (2019) -
Insulin and 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Differentially Regulate the Skeletal Muscle Cell Secretome
por: Gonzalez-Franquesa, Alba, et al.
Publicado: (2021) -
5-Amino-1-β-D-Ribofuranosyl-Imidazole-4-Carboxamide (AICAR) Reduces Peripheral Inflammation by Macrophage Phenotype Shift
por: Martin, Lisa Maria, et al.
Publicado: (2019) -
Dual control of NAD(+) synthesis by purine metabolites in yeast
por: Pinson, Benoît, et al.
Publicado: (2019) -
AICAR Antiproliferative Properties Involve the AMPK-Independent Activation of the Tumor Suppressors LATS 1 and 2
por: Philippe, Chloé, et al.
Publicado: (2018)