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The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy
CYP3A ranks among the most abundant cytochrome P450 enzymes in the liver, playing a dominant role in metabolic elimination of clinically used drugs. A main member in CYP3A family, CYP3A4 expression and activity vary considerably among individuals, attributable to genetic and non-genetic factors, aff...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901424/ https://www.ncbi.nlm.nih.gov/pubmed/24466438 http://dx.doi.org/10.3390/jpm2040175 |