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Poxvirus Viability and Signatures in Historical Relics
Although it has been >30 years since the eradication of smallpox, the unearthing of well-preserved tissue material in which the virus may reside has called into question the viability of variola virus decades or centuries after its original occurrence. Experimental data to address the long-term s...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Centers for Disease Control and Prevention
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901489/ https://www.ncbi.nlm.nih.gov/pubmed/24447382 http://dx.doi.org/10.3201/eid2002.131098 |
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author | McCollum, Andrea M. Li, Yu Wilkins, Kimberly Karem, Kevin L. Davidson, Whitni B. Paddock, Christopher D. Reynolds, Mary G. Damon, Inger K. |
author_facet | McCollum, Andrea M. Li, Yu Wilkins, Kimberly Karem, Kevin L. Davidson, Whitni B. Paddock, Christopher D. Reynolds, Mary G. Damon, Inger K. |
author_sort | McCollum, Andrea M. |
collection | PubMed |
description | Although it has been >30 years since the eradication of smallpox, the unearthing of well-preserved tissue material in which the virus may reside has called into question the viability of variola virus decades or centuries after its original occurrence. Experimental data to address the long-term stability and viability of the virus are limited. There are several instances of well-preserved corpses and tissues that have been examined for poxvirus viability and viral DNA. These historical specimens cause concern for potential exposures, and each situation should be approached cautiously and independently with the available information. Nevertheless, these specimens provide information on the history of a major disease and vaccination against it. |
format | Online Article Text |
id | pubmed-3901489 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-39014892014-02-01 Poxvirus Viability and Signatures in Historical Relics McCollum, Andrea M. Li, Yu Wilkins, Kimberly Karem, Kevin L. Davidson, Whitni B. Paddock, Christopher D. Reynolds, Mary G. Damon, Inger K. Emerg Infect Dis Synopsis Although it has been >30 years since the eradication of smallpox, the unearthing of well-preserved tissue material in which the virus may reside has called into question the viability of variola virus decades or centuries after its original occurrence. Experimental data to address the long-term stability and viability of the virus are limited. There are several instances of well-preserved corpses and tissues that have been examined for poxvirus viability and viral DNA. These historical specimens cause concern for potential exposures, and each situation should be approached cautiously and independently with the available information. Nevertheless, these specimens provide information on the history of a major disease and vaccination against it. Centers for Disease Control and Prevention 2014-02 /pmc/articles/PMC3901489/ /pubmed/24447382 http://dx.doi.org/10.3201/eid2002.131098 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Synopsis McCollum, Andrea M. Li, Yu Wilkins, Kimberly Karem, Kevin L. Davidson, Whitni B. Paddock, Christopher D. Reynolds, Mary G. Damon, Inger K. Poxvirus Viability and Signatures in Historical Relics |
title | Poxvirus Viability and Signatures in Historical Relics |
title_full | Poxvirus Viability and Signatures in Historical Relics |
title_fullStr | Poxvirus Viability and Signatures in Historical Relics |
title_full_unstemmed | Poxvirus Viability and Signatures in Historical Relics |
title_short | Poxvirus Viability and Signatures in Historical Relics |
title_sort | poxvirus viability and signatures in historical relics |
topic | Synopsis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901489/ https://www.ncbi.nlm.nih.gov/pubmed/24447382 http://dx.doi.org/10.3201/eid2002.131098 |
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