Cargando…
Implications of sex-specific selection for the genetic basis of disease
Mutation and selection are thought to shape the underlying genetic basis of many common human diseases. However, both processes depend on the context in which they occur, such as environment, genetic background, or sex. Sex has widely known effects on phenotypic expression of genotype, but an analys...
Autores principales: | Morrow, Edward H, Connallon, Tim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Ltd
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901550/ https://www.ncbi.nlm.nih.gov/pubmed/24478802 http://dx.doi.org/10.1111/eva.12097 |
Ejemplares similares
-
Sex-Differential Selection and the Evolution of X Inactivation Strategies
por: Connallon, Tim, et al.
Publicado: (2013) -
Association between Sex-Biased Gene Expression and Mutations with Sex-Specific Phenotypic Consequences in Drosophila
por: Connallon, Tim, et al.
Publicado: (2011) -
Polygenic signals of sex differences in selection in humans from the UK Biobank
por: Ruzicka, Filip, et al.
Publicado: (2022) -
Cross‐sex genetic correlations for fitness and fitness components: Connecting theoretical predictions to empirical patterns
por: Connallon, Tim, et al.
Publicado: (2019) -
Dominance reversals and the maintenance of genetic variation for fitness
por: Connallon, Tim, et al.
Publicado: (2019)