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Direct Observation of Heterogeneous Amyloid Fibril Growth Kinetics via Two-Color Super-Resolution Microscopy

[Image: see text] The self-assembly of normally soluble proteins into fibrillar amyloid structures is associated with a range of neurodegenerative disorders, such as Parkinson’s and Alzheimer’s diseases. In the present study, we show that specific events in the kinetics of the complex, multistep agg...

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Detalles Bibliográficos
Autores principales:	Pinotsi, Dorothea, Buell, Alexander K., Galvagnion, Celine, Dobson, Christopher M., Kaminski Schierle, Gabriele S., Kaminski, Clemens F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2013
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901574/ https://www.ncbi.nlm.nih.gov/pubmed/24303845 http://dx.doi.org/10.1021/nl4041093

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