BAG5 Protects against Mitochondrial Oxidative Damage through Regulating PINK1 Degradation

Mutations in PTEN-induced kinase 1 (PINK1) gene cause PARK6 familial Parkinsonism, and loss of the stability of PINK1 may also contribute to sporadic Parkinson's disease (PD). Degradation of PINK1 occurs predominantly through the ubiquitin proteasome system (UPS), however, to date, few of the p...

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Detalles Bibliográficos
Autores principales: Wang, Xuejing, Guo, Jifeng, Fei, Erkang, Mu, Yingfeng, He, Shuang, Che, Xiangqian, Tan, Jieqiong, Xia, Kun, Zhang, Zhuohua, Wang, Guanghui, Tang, Beisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901670/
https://www.ncbi.nlm.nih.gov/pubmed/24475098
http://dx.doi.org/10.1371/journal.pone.0086276

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