Impact of Measurement Error on Testing Genetic Association with Quantitative Traits

Measurement error of a phenotypic trait reduces the power to detect genetic associations. We examined the impact of sample size, allele frequency and effect size in presence of measurement error for quantitative traits. The statistical power to detect genetic association with phenotype mean and vari...

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Detalles Bibliográficos
Autores principales: Liao, Jiemin, Li, Xiang, Wong, Tien-Yin, Wang, Jie Jin, Khor, Chiea Chuen, Tai, E. Shyong, Aung, Tin, Teo, Yik-Ying, Cheng, Ching-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901720/
https://www.ncbi.nlm.nih.gov/pubmed/24475218
http://dx.doi.org/10.1371/journal.pone.0087044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901720/
https://www.ncbi.nlm.nih.gov/pubmed/24475218
http://dx.doi.org/10.1371/journal.pone.0087044

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