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Impact of Measurement Error on Testing Genetic Association with Quantitative Traits
Measurement error of a phenotypic trait reduces the power to detect genetic associations. We examined the impact of sample size, allele frequency and effect size in presence of measurement error for quantitative traits. The statistical power to detect genetic association with phenotype mean and vari...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901720/ https://www.ncbi.nlm.nih.gov/pubmed/24475218 http://dx.doi.org/10.1371/journal.pone.0087044 |