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PMA synergistically enhances apicularen A-induced cytotoxicity by disrupting microtubule networks in HeLa cells

BACKGROUND: Combination therapy is key to improving cancer treatment efficacy. Phorbol 12-myristate 13-acetate (PMA), a well-known PKC activator, increases the cytotoxicity of several anticancer drugs. Apicularen A induces cytotoxicity in tumor cells through disrupting microtubule networks by tubuli...

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Detalles Bibliográficos
Autores principales:	Seo, Kang-Sik, Kim, Jong-Seok, Park, Ji-Hoon, Song, Kyoung-Sub, Yun, Eun-Jin, Park, Jong-Il, Kweon, Gi Ryang, Yoon, Wan-Hee, Lim, Kyu, Hwang, Byung-Doo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901760/ https://www.ncbi.nlm.nih.gov/pubmed/24447339 http://dx.doi.org/10.1186/1471-2407-14-36

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