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Immunogenicity and safety of different formulations of an adjuvanted glycoprotein D genital herpes vaccine in healthy adults: A double-blind randomized trial

Herpes simplex virus (HSV) type 2 (HSV-2) is the main cause of genital and neonatal herpes and is highly prevalent worldwide. Previous phase I and II studies showed the immunogenicity and safety of the candidate prophylactic HSV-2 glycoprotein D-based subunit vaccine (gD2-AS04), containing aluminum...

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Detalles Bibliográficos
Autores principales: Leroux-Roels, Geert, Clément, Frédéric, Vandepapelière, Pierre, Fourneau, Marc, Heineman, Thomas, Dubin, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901814/
https://www.ncbi.nlm.nih.gov/pubmed/23434737
http://dx.doi.org/10.4161/hv.24043