Advances in targeting the vacuolar proton-translocating ATPase (V-ATPase) for anti-fungal therapy

Vacuolar proton-translocating ATPase (V-ATPase) is a membrane-bound, multi-subunit enzyme that uses the energy of ATP hydrolysis to pump protons across membranes. V-ATPase activity is critical for pH homeostasis and organelle acidification as well as for generation of the membrane potential that dri...

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Detalles Bibliográficos
Autores principales: Hayek, Summer R., Lee, Samuel A., Parra, Karlett J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902353/
https://www.ncbi.nlm.nih.gov/pubmed/24478704
http://dx.doi.org/10.3389/fphar.2014.00004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902353/
https://www.ncbi.nlm.nih.gov/pubmed/24478704
http://dx.doi.org/10.3389/fphar.2014.00004

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