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Advances in targeting the vacuolar proton-translocating ATPase (V-ATPase) for anti-fungal therapy
Vacuolar proton-translocating ATPase (V-ATPase) is a membrane-bound, multi-subunit enzyme that uses the energy of ATP hydrolysis to pump protons across membranes. V-ATPase activity is critical for pH homeostasis and organelle acidification as well as for generation of the membrane potential that dri...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902353/ https://www.ncbi.nlm.nih.gov/pubmed/24478704 http://dx.doi.org/10.3389/fphar.2014.00004 |