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Effect of Low Power Laser on Incisional Wound Healing

INTRODUCTION: The effectiveness of low power lasers for incisional wound healing, because of conflicting results of previous research studies, is uncertain. Therefore, this study was carried out to evaluate low power laser effects on incisional wound healing. MATERIALS AND METHODS: Incisional wound...

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Autores principales: Parirokh, Masoud, Dabiri, Shahriar, Bahrampour, AliReza, Homayon Zadeh, Mahmoud, Eghbal, Mohammad Jafar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Center for Endodontic Research 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902452/
https://www.ncbi.nlm.nih.gov/pubmed/24470799
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author Parirokh, Masoud
Dabiri, Shahriar
Bahrampour, AliReza
Homayon Zadeh, Mahmoud
Eghbal, Mohammad Jafar
author_facet Parirokh, Masoud
Dabiri, Shahriar
Bahrampour, AliReza
Homayon Zadeh, Mahmoud
Eghbal, Mohammad Jafar
author_sort Parirokh, Masoud
collection PubMed
description INTRODUCTION: The effectiveness of low power lasers for incisional wound healing, because of conflicting results of previous research studies, is uncertain. Therefore, this study was carried out to evaluate low power laser effects on incisional wound healing. MATERIALS AND METHODS: Incisional wound was produced on thirty-six mature male guinea pigs under general and local anesthesia. In half of the cases, He-Ne laser radiations were used for five minutes and the rest were left untreated. Animals were divided into six groups of six animals each that were killed after 3, 5 and 14 days. After histopathology processing and H&E staining, specimens were examined for acute and chronic inflammations, epithelial cell migration, epithelial seal and barrier formation, fibroblast migration, fibrosis, clot formation and granulation tissue formation. Mann-Whitney U and the Wilcoxon tests were used for statistical analysis. RESULTS: Statistically significant differences were found between fibroblast migration, acute and chronic inflammation of radiated groups and the control group at 5 days interval (p<0.05). There was no statistically significant difference at 3 and 14 days between laser radiated and control groups. CONCLUSION: This study showed that He-Ne laser had beneficial effects on incisional wound healing particularly at 5 days interval; however, further research on chronic ulcers is recommended.
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spelling pubmed-39024522014-01-27 Effect of Low Power Laser on Incisional Wound Healing Parirokh, Masoud Dabiri, Shahriar Bahrampour, AliReza Homayon Zadeh, Mahmoud Eghbal, Mohammad Jafar Iran Endod J Original Article INTRODUCTION: The effectiveness of low power lasers for incisional wound healing, because of conflicting results of previous research studies, is uncertain. Therefore, this study was carried out to evaluate low power laser effects on incisional wound healing. MATERIALS AND METHODS: Incisional wound was produced on thirty-six mature male guinea pigs under general and local anesthesia. In half of the cases, He-Ne laser radiations were used for five minutes and the rest were left untreated. Animals were divided into six groups of six animals each that were killed after 3, 5 and 14 days. After histopathology processing and H&E staining, specimens were examined for acute and chronic inflammations, epithelial cell migration, epithelial seal and barrier formation, fibroblast migration, fibrosis, clot formation and granulation tissue formation. Mann-Whitney U and the Wilcoxon tests were used for statistical analysis. RESULTS: Statistically significant differences were found between fibroblast migration, acute and chronic inflammation of radiated groups and the control group at 5 days interval (p<0.05). There was no statistically significant difference at 3 and 14 days between laser radiated and control groups. CONCLUSION: This study showed that He-Ne laser had beneficial effects on incisional wound healing particularly at 5 days interval; however, further research on chronic ulcers is recommended. Iranian Center for Endodontic Research 2006 2006-07-01 /pmc/articles/PMC3902452/ /pubmed/24470799 Text en © 2006, Iranian Center for Endodontic Research This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Parirokh, Masoud
Dabiri, Shahriar
Bahrampour, AliReza
Homayon Zadeh, Mahmoud
Eghbal, Mohammad Jafar
Effect of Low Power Laser on Incisional Wound Healing
title Effect of Low Power Laser on Incisional Wound Healing
title_full Effect of Low Power Laser on Incisional Wound Healing
title_fullStr Effect of Low Power Laser on Incisional Wound Healing
title_full_unstemmed Effect of Low Power Laser on Incisional Wound Healing
title_short Effect of Low Power Laser on Incisional Wound Healing
title_sort effect of low power laser on incisional wound healing
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902452/
https://www.ncbi.nlm.nih.gov/pubmed/24470799
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