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Kinase domain mutations and responses to dose escalation in chronic myeloid leukemia resistant to standard dose imatinib mesylate
Imatinib has shown unprecendeted success in the treatment of chronic myeloid leukemia (CML). However, over few years there have been reports regarding the primary and secondary resistance to Imatinib dampening the overall outcome in CML patients. In this study we have tried to assess the effect of d...
Autores principales: | Rajappa, Senthil, Mallavarapu, Krishna Mohan, Gundeti, Sadashivudu, Paul, Tara Roshni, Jacob, Rachel Thomas, Digumarti, Raghunadharao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902631/ https://www.ncbi.nlm.nih.gov/pubmed/24516316 http://dx.doi.org/10.4103/0971-5851.123750 |
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