Infarct size reduction by cyclosporine A at reperfusion involves inhibition of the mitochondrial permeability transition pore but does not improve mitochondrial respiration

INTRODUCTION: Ischemic postconditioning (PoCo) and cyclosporine A (CysA) given prior to reperfusion reduce myocardial infarct size after ischemia/reperfusion. Ischemic postconditioning's protection is characterized by better preservation of mitochondrial respiration and calcium retention capaci...

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Detalles Bibliográficos
Autores principales: Gedik, Nilguen, Heusch, Gerd, Skyschally, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2013
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902704/
https://www.ncbi.nlm.nih.gov/pubmed/24482638
http://dx.doi.org/10.5114/aoms.2013.38175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902704/
https://www.ncbi.nlm.nih.gov/pubmed/24482638
http://dx.doi.org/10.5114/aoms.2013.38175

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