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Programmable folding of fusion RNA in vivo and in vitro driven by pRNA 3WJ motif of phi29 DNA packaging motor

Misfolding and associated loss of function are common problems in constructing fusion RNA complexes due to changes in energy landscape and the nearest-neighbor principle. Here we report the incorporation and application of the pRNA-3WJ motif of the phi29 DNA packaging motor into fusion RNA with cont...

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Detalles Bibliográficos
Autores principales: Shu, Dan, Khisamutdinov, Emil F., Zhang, Le, Guo, Peixuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902900/
https://www.ncbi.nlm.nih.gov/pubmed/24084081
http://dx.doi.org/10.1093/nar/gkt885