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REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer

The androgen receptor (AR) is a key regulator of prostate tumorgenesis through actions that are not fully understood. We identified the repressor element (RE)-1 silencing transcription factor (REST) as a mediator of AR actions on gene repression. Chromatin immunoprecipitation showed that AR binds ch...

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Detalles Bibliográficos
Autores principales: Svensson, Charlotte, Ceder, Jens, Iglesias-Gato, Diego, Chuan, Yin-Choy, Pang, See Tong, Bjartell, Anders, Martinez, Roxana Merino, Bott, Laura, Helczynski, Leszek, Ulmert, David, Wang, Yuzhuo, Niu, Yuanjie, Collins, Colin, Flores-Morales, Amilcar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902919/
https://www.ncbi.nlm.nih.gov/pubmed/24163104
http://dx.doi.org/10.1093/nar/gkt921

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