Cargando…
REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer
The androgen receptor (AR) is a key regulator of prostate tumorgenesis through actions that are not fully understood. We identified the repressor element (RE)-1 silencing transcription factor (REST) as a mediator of AR actions on gene repression. Chromatin immunoprecipitation showed that AR binds ch...
Autores principales: | Svensson, Charlotte, Ceder, Jens, Iglesias-Gato, Diego, Chuan, Yin-Choy, Pang, See Tong, Bjartell, Anders, Martinez, Roxana Merino, Bott, Laura, Helczynski, Leszek, Ulmert, David, Wang, Yuzhuo, Niu, Yuanjie, Collins, Colin, Flores-Morales, Amilcar |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902919/ https://www.ncbi.nlm.nih.gov/pubmed/24163104 http://dx.doi.org/10.1093/nar/gkt921 |
Ejemplares similares
-
Elevated Level of Wnt5a Protein in Localized Prostate Cancer Tissue Is Associated with Better Outcome
por: Syed Khaja, Azharuddin Sajid, et al.
Publicado: (2011) -
Cystatin C Is Downregulated in Prostate Cancer and Modulates Invasion of Prostate Cancer Cells via MAPK/Erk and Androgen Receptor Pathways
por: Wegiel, Barbara, et al.
Publicado: (2009) -
Automatic registration of multi-modal microscopy images for integrative analysis of prostate tissue sections
por: Lippolis, Giuseppe, et al.
Publicado: (2013) -
OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo
por: Iglesias-Gato, Diego, et al.
Publicado: (2015) -
miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients
por: Hagman, Z, et al.
Publicado: (2013)