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Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases

In many bacteria and archaea, small RNAs derived from clustered regularly interspaced short palindromic repeats (CRISPRs) associate with CRISPR-associated (Cas) proteins to target foreign DNA for destruction. In Type I and III CRISPR/Cas systems, the Cas6 family of endoribonucleases generates functi...

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Detalles Bibliográficos
Autores principales:	Niewoehner, Ole, Jinek, Martin, Doudna, Jennifer A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902920/ https://www.ncbi.nlm.nih.gov/pubmed/24150936 http://dx.doi.org/10.1093/nar/gkt922

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