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Engineered reversal of drug resistance in cancer cells—metastases suppressor factors as change agents
Building molecular correlates of drug resistance in cancer and exploiting them for therapeutic intervention remains a pressing clinical need. To identify factors that impact drug resistance herein we built a model that couples inherent cell-based response toward drugs with transcriptomes of resistan...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902936/ https://www.ncbi.nlm.nih.gov/pubmed/24157835 http://dx.doi.org/10.1093/nar/gkt946 |