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Detection of G-quadruplex DNA in mammalian cells

It has been proposed that guanine-rich DNA forms four-stranded structures in vivo called G-quadruplexes or G4 DNA. G4 DNA has been implicated in several biological processes, but tools to study G4 DNA structures in cells are limited. Here we report the development of novel murine monoclonal antibodi...

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Detalles Bibliográficos
Autores principales: Henderson, Alexander, Wu, Yuliang, Huang, Yu Chuan, Chavez, Elizabeth A., Platt, Jesse, Johnson, F. Brad, Brosh, Robert M., Sen, Dipankar, Lansdorp, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902944/
https://www.ncbi.nlm.nih.gov/pubmed/24163102
http://dx.doi.org/10.1093/nar/gkt957