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Replication factors transiently associate with mtDNA at the mitochondrial inner membrane to facilitate replication
Mitochondrial DNA (mtDNA) is organized in discrete protein–DNA complexes, nucleoids, that are usually considered to be mitochondrial-inner-membrane associated. Here we addressed the association of replication factors with nucleoids and show that endogenous mtDNA helicase Twinkle and single-stranded...
Autores principales: | Rajala, Nina, Gerhold, Joachim M., Martinsson, Peter, Klymov, Alexey, Spelbrink, Johannes N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902951/ https://www.ncbi.nlm.nih.gov/pubmed/24163258 http://dx.doi.org/10.1093/nar/gkt988 |
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