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Replication factors transiently associate with mtDNA at the mitochondrial inner membrane to facilitate replication

Mitochondrial DNA (mtDNA) is organized in discrete protein–DNA complexes, nucleoids, that are usually considered to be mitochondrial-inner-membrane associated. Here we addressed the association of replication factors with nucleoids and show that endogenous mtDNA helicase Twinkle and single-stranded...

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Detalles Bibliográficos
Autores principales: Rajala, Nina, Gerhold, Joachim M., Martinsson, Peter, Klymov, Alexey, Spelbrink, Johannes N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902951/
https://www.ncbi.nlm.nih.gov/pubmed/24163258
http://dx.doi.org/10.1093/nar/gkt988

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