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Kisspeptin Restores Pulsatile LH Secretion in Patients with Neurokinin B Signaling Deficiencies: Physiological, Pathophysiological and Therapeutic Implications

Pulsatile gonadotropin-releasing hormone (GnRH) is crucial to normal reproductive function and abnormalities in pulse frequency give rise to reproductive dysfunction. Kisspeptin and neurokinin B (NKB), neuropeptides secreted by the same neuronal population in the ventral hypothalamus, have emerged r...

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Detalles Bibliográficos
Autores principales: Young, Jacques, George, Jyothis T., Tello, Javier A., Francou, Bruno, Bouligand, Jerome, Guiochon-Mantel, Anne, Brailly-Tabard, Sylvie, Anderson, Richard A., Millar, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902960/
https://www.ncbi.nlm.nih.gov/pubmed/22377698
http://dx.doi.org/10.1159/000336376